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FOX04-DRI (10mg Vial) Questions Answered

FOXO4-DRI (also known as Proxofim) is a synthetic D-retro-inverso peptide designed to selectively induce apoptosis in senescent cells by disrupting the FOXO4–p53 protein interaction [1] [2] .

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FOX04-DRI (10mg Vial)

Week Daily Dose (mcg) Units (per injection) (mL) Weeks 1–4 250 mcg 7.5 units (0.075 mL) Weeks 5–8 375 mcg 11 units (0.11 mL) Weeks 9–12 500 mcg 15 units (0.15 mL) Weeks 13–16 500 mcg 15 units (0.15 mL) Frequency: Inject once daily subcutaneously [7] .

Quickstart Highlights

FOXO4-DRI (also known as Proxofim) is a synthetic D-retro-inverso peptide designed to selectively induce apoptosis in senescent cells by disrupting the FOXO4–p53 protein interaction [1] [2] .

Standard / Gradual Approach (3 mL = ~3.33 mg/mL)

Week Daily Dose (mcg) Units (per injection) (mL) Weeks 1–4 250 mcg 7.5 units (0.075 mL) Weeks 5–8 375 mcg 11 units (0.11 mL) Weeks 9–12 500 mcg 15 units (0.15 mL) Weeks 13–16 500 mcg 15 units (0.15 mL) Frequency: Inject once daily subcutaneously [7] .

Supplies Needed

Plan based on an 8–16 week daily protocol with gradual titration.

Important Notes

Practical considerations for consistency and safety. Use new sterile insulin syringes (typically 29–31 gauge, 0.5 inch needle) for each injection [9] ; dispose in a sharps container.