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PE-22-28 (10mg Vial) Questions Answered

PE-22-28 is a synthetic heptapeptide (sequence: GVSWGLR) derived from the sortilin propeptide, engineered as a potent and selective antagonist of TREK-1 potassium channels [4] .

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PE-22-28 (10mg Vial)

Week Daily Dose (µg) Units (per injection) (mL) Weeks 1–2 50 µg 1.5 units (0.015 mL) Weeks 3–4 100 µg 3 units (0.03 mL) Weeks 5–8 100 µg 3 units (0.03 mL) Weeks 9–12 (Optional) 150 µg 4.5 units (0.045 mL) Weeks 13–16 (Optional) 200 µg 6 units (0.06 mL) Freq...

Quickstart Highlights

PE-22-28 is a synthetic heptapeptide (sequence: GVSWGLR) derived from the sortilin propeptide, engineered as a potent and selective antagonist of TREK-1 potassium channels [4] .

Standard / Gradual Approach (3 mL = ~3.33 mg/mL)

Week Daily Dose (µg) Units (per injection) (mL) Weeks 1–2 50 µg 1.5 units (0.015 mL) Weeks 3–4 100 µg 3 units (0.03 mL) Weeks 5–8 100 µg 3 units (0.03 mL) Weeks 9–12 (Optional) 150 µg 4.5 units (0.045 mL) Weeks 13–16 (Optional) 200 µg 6 units (0.06 mL) Freq...

Supplies Needed

Plan based on an 8–16 week daily protocol with gradual titration. Replace vials every 4 weeks to maintain potency.

Storage Instructions

Proper storage preserves peptide quality and potency. Lyophilized: Store at −20 °C (−4 °F) in dry, dark conditions; minimize moisture exposure.