Compound Library

Medication / Glucose/Longevity

Acarbose

Alpha-glucosidase inhibitor that slows carbohydrate digestion — blunts post-meal glucose spikes. Remarkable longevity data in ITP mouse trials (significant lifespan extension). Bryan Johnson protocol includes 200mg with largest meal. Reduces cardiovascular events in non-diabetics.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose25–100mg oral with first bite of meals.
Half-life2 hours
Risk flaglow
Regulatory noteFDA-approved context noted

Side effects and watch-outs

  • Flatulence (very common — start low and titrate)
  • Bloating
  • Diarrhea
  • Abdominal pain
  • Improves with dietary low-carb adaptation