Compound Library

Supplement / Performance

Agmatine Sulfate

Arginine metabolite. Nitric oxide regulation, analgesic, neuroprotective, and insulin sensitising. Synergistic with citrulline for pump. Also used for opioid withdrawal management.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose500–2000 mg/day (1–2g pre-workout)
Half-life2 hours
Risk flaglow
Regulatory noteReview required

Side effects and watch-outs

  • GI distress (nausea, diarrhoea at high doses)
  • Headache
  • Dizziness
  • ⚠️ Potential interaction with diabetes medications (insulin sensitising)
  • Generally well tolerated