Compound Library

Supplement / Antioxidant

Alpha-Lipoic Acid (ALA)

Universal antioxidant — soluble in both water and fat. Regenerates other antioxidants (vitamins C, E, glutathione). Improves insulin sensitivity. Used with glucose-disposing agents.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose300–600 mg/day with meals
Half-life3 hours
Risk flaglow
Regulatory noteReview required

Side effects and watch-outs

  • GI distress on empty stomach
  • Thiamine (B1) depletion with chronic high-dose use
  • Mild blood sugar lowering
  • Rare: skin rash
  • Rare: thyroid disruption at very high doses