Compound Library

Supplement / NAD+/Longevity

Apigenin

Flavonoid that inhibits CD38 (an enzyme that degrades NAD+). Synergistic with NMN — preserves NAD+ by blocking its degradation. Found in chamomile tea. Anti-inflammatory, anxiolytic, may extend lifespan via NAD+ preservation.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose50–100mg oral daily.
Half-life8 hours
Risk flaglow
Regulatory noteReview required

Side effects and watch-outs

  • Very well tolerated
  • Mild sedation at high doses
  • Potential interaction with CYP enzymes