Compound Library

Peptide / Aesthetic

Argireline (Acetyl Hexapeptide-3)

Most studied anti-wrinkle neuropeptide. Inhibits neurotransmitter release at neuromuscular junction. Reduces dynamic wrinkle depth by 17–30% in clinical studies. First-in-class topical wrinkle relaxer.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference doseApplied topically at 5–10% concentration. Morning and evening.
Half-life0.5 hours
Risk flaglow
Regulatory noteReview required

Side effects and watch-outs

  • Very well tolerated
  • Rare: contact sensitivity
  • Mild local redness initially