Compound Library

Ancillary / Cardiovascular

Carvedilol

Non-selective beta-blocker with alpha-1 blocking activity. Cardioprotective on high-dose AAS. Used by performance users for heart rate, blood pressure, and cardiac remodelling mitigation.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose3.125–25 mg twice daily
Half-life8 hours
Risk flagmoderate
Regulatory noteFDA-approved context noted

Side effects and watch-outs

  • Bradycardia (slowed heart rate)
  • Fatigue
  • Dizziness
  • Cold extremities
  • Blunts exercise heart rate response
  • ⚠️ Exacerbates asthma/COPD — contraindicated in reactive airway disease
  • Do not stop abruptly — taper