Ancillary / SERM

Clomiphene (Clomid)

SERM that stimulates LH/FSH by blocking hypothalamic/pituitary oestrogen receptors. Standard PCT medication. Contains both active (Enclomiphene) and problematic (Zuclomiphene) isomers.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.

Reference dosePCT: 25–50 mg/day for 4–6 weeks

Half-life120 hours

Risk flagmoderate

Regulatory noteFDA-approved context noted

Side effects and watch-outs

⚠️ Visual disturbances — floaters, blurred vision, visual field changes
⚠️ DISCONTINUE immediately if any visual symptoms — risk of irreversible ocular damage
Mood changes and emotional lability
Hot flushes
Headache
Nausea
Rare: ovarian hyperstimulation in women