Compound Library

Supplement / Mitochondrial

CoQ10 (Ubiquinone / Ubiquinol)

Mitochondrial coenzyme essential for cellular energy production. Declines with age and depleted by statins. Ubiquinol (reduced form) is better absorbed than ubiquinone. Critical for cardiovascular health and mitochondrial function.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference doseUbiquinol: 100–300 mg/day with fat. Ubiquinone: 200–600 mg/day with fat
Half-life24 hours
Risk flaglow
Regulatory noteReview required

Side effects and watch-outs

  • GI upset (nausea, diarrhoea) at high doses
  • Insomnia if taken late at night
  • Mild blood pressure lowering (beneficial or may cause dizziness)
  • May interact with warfarin — monitor INR
  • Generally very well tolerated