Compound Library

Peptide / Longevity

Dihexa

Potent HGF/Met activator derived from angiotensin IV. Promotes synaptogenesis and neurogenesis. Estimated millions of times more potent than BDNF in preclinical models. Long half-life — accumulates.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose0.1–1 mg oral or SubQ per day
Half-life24 hours
Risk flagmoderate
Regulatory noteResearch-only flag

Side effects and watch-outs

  • Cognitive overwhelm or anxiety at higher doses
  • Insomnia
  • Very limited human safety data
  • Long half-life means accumulation — slow careful escalation essential