Ancillary / DHT Blocker

Dutasteride (Avodart)

Dual 5-alpha reductase inhibitor. FDA-approved for BPH. More potent than Finasteride — reduces DHT by ~99%. Used for aggressive hair preservation. Extremely long half-life.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.

Reference dose0.5 mg/day

Half-life840 hours

Risk flagmoderate

Regulatory noteFDA-approved context noted

Side effects and watch-outs

Same as Finasteride but more pronounced due to greater DHT suppression
Sexual dysfunction (more common than Finasteride)
⚠️ Post-Dutasteride syndrome (same concern as Post-Finasteride Syndrome)
Gynaecomastia
Very long half-life (5+ weeks) — effects persist long after stopping
Rare: liver injury