Side effects and watch-outs
- Generally very well tolerated
- GI upset at high doses
- Mild headache
- Limited long-term human data
- Piperine (black pepper extract) increases bioavailability significantly
Supplement / Longevity
Fisetin
Flavonoid with potent senolytic (senescent cell-clearing) properties. Among the most potent senolytics identified. Pulse dosing protocol (higher dose for 2–3 consecutive days monthly) mirrors clinical research.
Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.