Compound Library

Supplement / Cardiovascular

Grape Seed Extract (OPC)

Oligomeric proanthocyanidins from grape seeds. Potent antioxidant, anti-inflammatory, vasodilatory. Used for blood pressure support and cardiovascular protection on cycle.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose150–300 mg/day
Half-life8 hours
Risk flaglow
Regulatory noteReview required

Side effects and watch-outs

  • GI distress
  • Headache
  • Rare: allergic reaction in grape/wine sensitive individuals
  • Mild anticoagulant effect — caution pre-surgery
  • Generally very well tolerated