Compound Library

Supplement / Performance

HMB (β-Hydroxy β-Methylbutyrate)

Leucine metabolite. Anti-catabolic — reduces muscle protein breakdown. Most effective during caloric deficit or high training volumes. Free acid form (HMB-FA) has superior absorption vs Calcium HMB.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose3 g/day (HMB-FA form: 2 g/day)
Half-life3 hours
Risk flaglow
Regulatory noteReview required

Side effects and watch-outs

  • Generally extremely well tolerated
  • Mild GI distress
  • Headache (uncommon)
  • Effects modest compared to AAS/SARMs — realistic expectations required