Compound Library

Supplement / Performance

Icariin (Horny Goat Weed)

PDE5 inhibitor from Epimedium. Natural Viagra-like mechanism. Also mild 5-alpha reductase inhibitor and androgen receptor agonist. Evidence for bone density and testosterone support.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose500–2000 mg/day (standardised 40–60% icariin)
Half-life4 hours
Risk flaglow
Regulatory noteReview required

Side effects and watch-outs

  • Dizziness
  • Dry mouth
  • Headache
  • ⚠️ Tachycardia at high doses
  • Potential interaction with anticoagulants
  • ⚠️ Mild PDE5 inhibition — do not combine with pharmaceutical PDE5 inhibitors or nitrates