Compound Library

Blend / GnRH

Kisspeptin + GnRH Protocol

Advanced HPTA restart protocol. Kisspeptin stimulates GnRH release; exogenous pulsatile GnRH then stimulates LH/FSH. Used for severe post-cycle hypogonadism or TRT cessation.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference doseKisspeptin: 1–6 nmol/kg SubQ + Gonadorelin: 100 mcg pulsatile 2x daily
Half-life0.25 hours
Risk flagmoderate
Regulatory noteResearch-only flag

Side effects and watch-outs

  • LH/FSH surge — ovarian hyperstimulation risk in women
  • Nausea
  • Headache
  • Testicular discomfort from LH surge
  • Requires endocrine supervision for optimal dosing