Compound Library

Peptide / Anti-Inflammatory

KPV

C-terminal tripeptide of α-MSH. Potent anti-inflammatory with affinity for gut and skin. Notably orally bioavailable for a peptide. Used for IBD, inflammatory skin conditions, and wound healing.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose500 mcg – 2 mg SubQ or oral daily
Half-life0.5 hours
Risk flaglow
Regulatory noteResearch-only flag

Side effects and watch-outs

  • Generally very well tolerated
  • Mild injection site reaction
  • Rare: transient hypotension at high IV doses
  • Very limited long-term human clinical data