Peptide / Metabolic

LEAP2 (Liver-Expressed Antimicrobial Peptide 2)

Endogenous GHSR antagonist — blocks the ghrelin receptor. Reduces appetite by opposing ghrelin. Inverse relationship to fasting — elevated when fed. Research into metabolic syndrome and obesity.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.

Reference doseResearch only — no established dosing

Half-life1.5 hours

Risk flagmoderate

Regulatory noteResearch-only flag

Side effects and watch-outs

Appetite suppression
Nausea
No established human protocol
Early research stage