Peptide / Sexual Health

Melanotan I (Afamelanotide)

Selective MC1R agonist (Scenesse). FDA-approved for erythropoietic protoporphyria. No MC4R activity = no libido or erection effects. Much safer than MT-2.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.

Reference dose16 mg SC implant every 2 months (FDA); 0.5–1 mg SubQ daily (research)

Half-life1 hours

Risk flaglow

Regulatory noteFDA-approved context noted

Side effects and watch-outs

Nausea (mild)
Skin hyperpigmentation
Headache
Fatigue
Injection site reaction
Mole darkening — monitor
Freckle formation
Much safer than MT-2