Compound Library
Supplement / Longevity
NMN (Nicotinamide Mononucleotide)
NAD+ precursor restoring declining NAD+ levels with age. Activates sirtuins (SIRT1-7) and PARPs for DNA repair. Phase 2 trials confirm safety and NAD+ elevation. Take in the morning.
Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Side effects and watch-outs
- Nausea at high doses
- Headache on initiation
- Flushing (less than NR or niacin)
- Insomnia if taken in evening
- Theoretical: NAMPT upregulation may support existing cancer growth — avoid with active cancer
- Generally very well tolerated up to 1200 mg/day in trials
