Compound Library

Peptide / Cognitive

P21 Peptide

CNTF analog. Stimulates hippocampal neurogenesis without receptor downregulation. Experimental — very limited human data. Used intranasally.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose50–100 mcg intranasal daily
Half-life1 hours
Risk flagmoderate
Regulatory noteResearch-only flag

Side effects and watch-outs

  • Extremely limited human safety data
  • Potential CNS overstimulation
  • Headache
  • Nasal irritation
  • Unknown long-term effects