Compound Library

Supplement / Anti-inflammatory/Pain

Palmitoylethanolamide (PEA)

Endocannabinoid-like lipid mediator with potent anti-inflammatory and analgesic properties. Acts on PPAR-alpha and mast cells. Clinical evidence for neuropathic pain, fibromyalgia, and chronic inflammation. Excellent safety profile. Synergistic with BPC-157 for injury protocols.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose300–600mg oral twice daily.
Half-life12 hours
Risk flaglow
Regulatory noteReview required

Side effects and watch-outs

  • Generally extremely well tolerated
  • Mild GI upset
  • Headache (rare)