Compound Library

Medication / Joint Health

Pentosan Polysulfate (PPS)

Heparin-like compound with anti-inflammatory effects on joint tissue. FDA-approved for interstitial cystitis. Growing research for osteoarthritis — may restore cartilage and reduce joint degradation. Used in protocols alongside BPC-157 for joint healing.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose100mg oral 3x daily (IC). Joint protocol: may vary.
Half-life5 hours
Risk flaglow
Regulatory noteFDA-approved context noted

Side effects and watch-outs

  • GI distress
  • Headache
  • Alopecia (hair loss — dose-dependent, reversible)
  • Rare: retinal maculopathy with long-term high-dose use
  • Bruising