Compound Library

Supplement / Cognitive

Phosphatidylserine

Phospholipid component of cell membranes — especially high in brain. Reduces cortisol, improves cognitive function, and may support testosterone in athletes. Neuroprotective.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose300–800 mg/day (with meals)
Half-life12 hours
Risk flaglow
Regulatory noteReview required

Side effects and watch-outs

  • GI distress at high doses
  • Insomnia (uncommon)
  • Generally well tolerated
  • Rare: blood thinning at very high doses — caution pre-surgery