Ancillary / Dopamine Agonist

Pramipexole (Prami)

Dopamine D3/D2 agonist. More potent dopamine agonist than Cabergoline for prolactin control. Shorter half-life. FDA-approved for Parkinson's and restless legs.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.

Reference dose0.125–0.5 mg at bedtime

Half-life8 hours

Risk flagmoderate

Regulatory noteFDA-approved context noted

Side effects and watch-outs

Strong sedation (take at bedtime)
Nausea
Dizziness
⚠️ Compulsive behaviours (gambling, hypersexuality — more common than with Cabergoline)
Orthostatic hypotension
Do not abruptly discontinue
Avoid alcohol