Compound Library
Ancillary / Anti-androgen
Spironolactone
Aldosterone antagonist and anti-androgen. FDA-approved for heart failure and hypertension. Also used for acne, hair loss, and female pattern baldness. Potassium-sparing diuretic.
Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Side effects and watch-outs
- ⚠️ Hyperkalaemia (elevated potassium — dangerous in kidney disease)
- Gynaecomastia in men (anti-androgenic — feminising in men)
- Menstrual irregularities in women
- Dizziness/orthostatic hypotension
- Frequent urination
- ⚠️ Contraindicated in kidney disease, hyperkalemia, Addison's disease
