Testosterone / Long Ester

Testosterone Enanthate

Gold standard for TRT and the most prescribed testosterone ester worldwide. Long ester provides stable serum levels with 1–2x weekly injections. Controlled substance — prescription required in most countries.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.

Reference doseTRT: 100–200 mg/week. Performance: 300–600 mg/week

Half-life168 hours

Risk flagmoderate

Regulatory noteFDA-approved context noted

Side effects and watch-outs

Oestrogen elevation → gynaecomastia, water retention
Acne and oily skin
Hair loss (DHT-mediated, genetically dependent)
Testicular atrophy and infertility
⚠️ Haematocrit elevation — polycythaemia risk (stroke, DVT)
Sleep apnoea
LDL↑ / HDL↓
Left ventricular hypertrophy at supraphysiological doses
Mood changes and aggression at high doses
⚠️ Full bloodwork every 6 months minimum (hormones, CBC, lipids, liver, PSA)