Compound Library

Testosterone / Very Long Ester

Testosterone Pellets (Testopel)

FDA-approved subcutaneous testosterone pellets implanted every 3–6 months. Smooth steady-state levels. Popular with women for low-dose TRT. Requires minor surgical procedure.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose150–450 mg implanted every 3–6 months (10–12 pellets per 75 mg)
Half-life1440 hours
Risk flagmoderate
Regulatory noteFDA-approved context noted

Side effects and watch-outs

  • Insertion site infection (rare)
  • Pellet extrusion (3–10%)
  • Fibrosis at insertion site
  • Oestrogen elevation
  • HPTA suppression
  • Cannot rapidly adjust dose once implanted
  • ⚠️ Irreversible for the duration once implanted