Compound Library

Testosterone / Oral

Testosterone Undecanoate (Jatenzo)

FDA-approved oral testosterone undecanoate. Absorbed via lymphatic system (requires fat). Twice-daily dosing with meals. Avoids liver first-pass. Blood pressure monitoring required.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose158–396 mg twice daily with a fat-containing meal
Half-life16 hours
Risk flagmoderate
Regulatory noteFDA-approved context noted

Side effects and watch-outs

  • ⚠️ Significant blood pressure elevation — daily BP monitoring required
  • Cardiovascular risk elevation
  • HPTA suppression
  • Oestrogen elevation
  • Haematocrit elevation
  • Must be taken with fat — poor absorption otherwise