Testosterone / Oral

Testosterone Undecanoate (Oral)

Oral TRT (Jatenzo/Kyzaleo). Absorbed via lymphatics — taken with meals. FDA-approved. 2x daily dosing. Lower androgenic impact than injections.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.

Reference dose158–396 mg twice daily with fatty meals

Half-life16 hours

Risk flagmoderate

Regulatory noteFDA-approved context noted

Side effects and watch-outs

Cardiovascular: may elevate blood pressure significantly
GI distress (must take with fat)
Oestrogen elevation
HPTA suppression
Haematocrit elevation
Inconvenient twice-daily dosing