Side effects and watch-outs
- Fishy body odour at high doses (trimethylamine — reduced with divided dosing)
- GI distress
- Nausea
- Potential cholesterol elevation at very high doses
- Generally well tolerated
Supplement / Performance
TMG (Trimethylglycine / Betaine)
Methyl donor and osmolyte. Evidence for homocysteine reduction, power output, and as a methyl donor alongside NMN/NAD+ protocols. Synergistic with methylfolate and methylcobalamin.
Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.