Compound Library

Ancillary / PDE5 Inhibitor

Vardenafil (Levitra)

FDA-approved PDE5 inhibitor. Similar duration to Sildenafil. Some evidence for more potency at equivalent doses. Heart-protective properties at low doses.

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Educational reference only. This page does not diagnose, prescribe, or replace care from a licensed professional. Laws, availability, and clinical appropriateness vary by location.
Reference dose5–20 mg as needed
Half-life4.5 hours
Risk flaglow
Regulatory noteFDA-approved context noted

Side effects and watch-outs

  • Headache
  • Flushing
  • Nasal congestion
  • Dizziness
  • Dyspepsia
  • ⚠️ CONTRAINDICATED with nitrates
  • ⚠️ Prolonged QT interval risk — avoid with antiarrhythmics
  • Hypotension