Cortagen (20mg Vial)

01 · At a glance

Quickstart Highlights

Cortagen is an ultrashort tetrapeptide Ala–Glu–Asp–Pro (AEDP) , synthesized as a defined fragment based on the bovine brain-cortex extract Cortexin. In research models it modulates gene expression and neuronal plasticity at microgram-per-kg ranges. Recognized research ranges: 0.01 mg/kg daily for ~10 days (i.m.) and 0.01–0.10 mg/kg daily for ~5 days (i.p.) in rodent models. Reconstitute to 3.0 mL (max vial capacity) to keep syringe measurements practical; 20 mg ÷ 3 mL = 6.67 mg/mL . At 6.67 mg/mL, 1 insulin “unit” (100-unit syringe) = 0.01 mL ≈ 0.0667 mg (66.7 µg) . Example (70 kg, model scaling): 0.01 mg/kg → 0.70 mg/day ≈ 10.5 units; 0.03 mg/kg → 2.10 mg/day ≈ 31.5 units. Storage: Lyophilized at −20 °C (−4 °F); after reconstitution 2–8 °C (36–46 °F), protected from light. For research use only. Not for human consumption or veterinary use.

02 · Dosing & reconstitution

Dosing & Reconstitution Guide

A practical calculator-ready setup based on the imported protocol reference. Use these values as a math starting point, then verify every entry against your own vial, diluent, and professional guidance.

Standard / Gradual Approach — 10-Day Course (3.0 mL = 6.67 mg/mL)

Reference dose shown on this page: See guide.

Advanced / Aggressive Approach

Reconstitution Steps

1. Confirm the vial amount, unit, and diluent amount before entering values in the calculator.
2. Add diluent slowly down the inner wall of the vial when reconstitution is appropriate for the compound.
3. Swirl or roll gently until dissolved; avoid shaking unless the product instructions specifically say otherwise.
4. Label the vial with the date and concentration, then store according to the protocol and product instructions.

03 · What you'll need

Supplies Needed

Keep this as a planning checklist. TNHL does not sell or verify supplies on this page, and no supplier quality claims are made here.

Protocol Overview

• Reconstitution: Use 3.0 mL to maintain ≥~10 units where feasible (6.67 mg/mL).
• Storage: Lyophilized −20 °C (−4 °F); reconstituted 2–8 °C (36–46 °F); protect from light.

Dosing Protocol

• Weight-scaled calculations for your lab model.
• Daily Dose Formula: 0.01–0.03 mg/kg (per cited models); compute mg and convert to units using 6.67 mg/mL.
• Frequency: Once daily during the selected course (5 or 10 days).
• Timing: Dose at a consistent daily time.
• Document weight, route, and exact volume.
• Route: Per study design; published models used i.m. (10-day) and i.p. (5-day).

Storage Instructions

• Lyophilized at −20 °C (−4 °F); after reconstitution 2–8 °C (36–46 °F), protected from light. For research use only. Not for human consumption or veterinary use.
• Storage: Lyophilized −20 °C (−4 °F); reconstituted 2–8 °C (36–46 °F); protect from light.
• Keep mixed and unmixed items clearly labeled so inventory and dose logs stay accurate.

04 · Good to know

Important Notes

• This Cortagen page is for educational research organization only.
• Confirm route, dose, contraindications, monitoring, storage, and cycle decisions with qualified professional guidance.
• Use sterile technique, rotate sites when applicable, and log missed doses, reactions, and inventory changes.

05 · How it works

How This Works

Cortagen is an ultrashort tetrapeptide Ala–Glu–Asp–Pro (AEDP) , synthesized as a defined fragment based on the bovine brain-cortex extract Cortexin.

In research models it modulates gene expression and neuronal plasticity at microgram-per-kg ranges.

Recognized research ranges: 0.01 mg/kg daily for ~10 days (i.m.) and 0.01–0.10 mg/kg daily for ~5 days (i.p.) in rodent models.

The library page pairs that educational context with calculator-ready vial math, so users can understand the protocol structure and then track their own entered values in one place.

06 · Daily habits

Lifestyle Factors

• Keep meals, training, sleep, and recovery notes in the journal so trends are easier to review.
• Track body metrics only if they are relevant to the user's goal and approved data sources.
• Use consistent timing and logging habits so adherence data is meaningful.

07 · What to expect

Potential Benefits & Side Effects

• Reported in preclinical literature (not clinical claims).
• Behavioral modulation in mice within the 0.01–0.10 mg/kg range (5-day courses).
• Enhanced nerve regeneration metrics in rat sciatic-injury models at 0.01 mg/kg (10-day course).
• Adverse effects data are limited; use standard lab safety, monitor animals per protocol.

08 · Technique

Injection Technique

09 · Evidence

References