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Protocol

Epithalon (10mg Vial)

Complete dosage protocol and reconstitution guide for Epithalon (10mg Vial).

Updated November 26, 2025 Research guide Research information only
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Educational reference only. TNHL calculates and organizes user-entered values; it does not diagnose, prescribe, recommend doses, or replace guidance from a qualified professional.
MechanismEpitalon (also known as Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed from the naturally occurring pineal peptide epithalamin [1] . Research indicates it may support telomerase activation, circadian rhythm regulation, and anti-aging pathways [2] [3] .
Dosing5–10 mg once daily (subcutaneous injection).
ReconstitutionAdd 2.0 mL diluent to a 10 mg vial.
StorageLyophilized: freeze at −20 °C (−4 °F) ; reconstituted: refrigerate at 2–8 °C (35.6–46.4 °F) ; avoid freeze–thaw cycles [9] [10] .

Calculator preset

Run the vial math before tracking.

At 5 mg/mL, 1 unit = 50 mcg ; 5 mg = 100 units (1.0 mL) and 10 mg = 200 units (2.0 mL) on a U-100 syringe.

Calculate this vial

01 · At a glance

Quickstart Highlights

Epitalon (also known as Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed from the naturally occurring pineal peptide epithalamin [1] . Research indicates it may support telomerase activation, circadian rhythm regulation, and anti-aging pathways [2] [3] . Clinical studies employ short intermittent cycles (10–20 days) repeated 1–2 times annually [4] , though extended titration protocols are also explored for research purposes.

ReconstituteAdd 2.0 mL bacteriostatic water → 5 mg/mL concentration (10 mg total).
Reference dose5–10 mg once daily (subcutaneous injection).
Easy measuringAt 5 mg/mL, 1 unit = 50 mcg ; 5 mg = 100 units (1.0 mL) and 10 mg = 200 units (2.0 mL) on a U-100 syringe.
StorageLyophilized: freeze at −20 °C (−4 °F) ; reconstituted: refrigerate at 2–8 °C (35.6–46.4 °F) ; avoid freeze–thaw cycles [9] [10] .
Start with sterile preparation, storage, and injection-site basics before using any calculator output. TNHL is a tracking and education tool only.

02 · Dosing & reconstitution

Dosing & Reconstitution Guide

A practical calculator-ready setup based on the imported protocol reference. Use these values as a math starting point, then verify every entry against your own vial, diluent, and professional guidance.

Standard Cyclic Protocol (2 mL = 5 mg/mL)

Phase / setup Dose & frequency Volume / units
Days 1–55 mg (5000 mcg)100 units (1.00 mL)
Days 6–105 mg (5000 mcg)100 units (1.00 mL)
Days 11–20(optional extension) 5–10 mg (5000–10000 mcg) 100–200 units (1.00–2.00 mL)

5–10 mg once daily (subcutaneous injection).

Reconstitution Steps

  1. Draw 2.0 mL bacteriostatic water with a sterile syringe.
  2. Inject slowly down the vial wall to avoid foaming.
  3. Gently swirl or roll until fully dissolved (do not shake vigorously).
  4. Label with reconstitution date and refrigerate at 2–8 °C (35.6–46.4 °F) , protected from light.
  5. Use within 2–4 weeks of reconstitution for optimal potency [9] .

03 · What you'll need

Supplies Needed

Keep this as a planning checklist. TNHL does not sell or verify supplies on this page, and no supplier quality claims are made here.

Peptide vial 10 mg
  • Match the label on the vial before calculating.
Diluent 2.0 mL
  • Use only the diluent appropriate for the compound and instructions.
Syringes U-100 or custom
  • Calculator output can be translated to syringe units.
Tracking Protocol Pal
  • Log dose dates, inventory, sites, and observations.

Protocol Overview

  • Goal: Support cellular health, telomere maintenance, and circadian rhythm regulation [2] [3] . Standard
  • Schedule: 10–20 day cycles of daily subcutaneous injections, repeated 1–2 times per year with 6–12 month breaks between cycles [4] [5] . Alternative Schedule: Extended titration protocols (8–16 weeks) for gradual dose escalation research.
  • Dose Range: 5–10 mg daily during active cycles or titration phases.
  • Reconstitution: 2.0 mL per 10 mg vial (5 mg/mL) for practical dosing volumes.
  • Storage: Lyophilized frozen at −20 °C (−4 °F); reconstituted refrigerated at 2–8 °C (35.6–46.4 °F); avoid repeated freeze–thaw cycles [9] .

Dosing Protocol

  • 5–10 mg once daily (subcutaneous injection).
  • Inject once daily subcutaneously during the active cycle. After completing 10–20 days, take a break of 6–12 months before repeating.
  • If values change, rerun the calculator and update the protocol so future logs match the active plan.

Storage Instructions

  • Lyophilized: freeze at −20 °C (−4 °F) ; reconstituted: refrigerate at 2–8 °C (35.6–46.4 °F) ; avoid freeze–thaw cycles [9] [10] .
  • Storage: Lyophilized frozen at −20 °C (−4 °F); reconstituted refrigerated at 2–8 °C (35.6–46.4 °F); avoid repeated freeze–thaw cycles [9] .
  • Keep mixed and unmixed items clearly labeled so inventory and dose logs stay accurate.

04 · Good to know

Important Notes

  • This Epithalon page is for educational research organization only.
  • Confirm route, dose, contraindications, monitoring, storage, and cycle decisions with qualified professional guidance.
  • Use sterile technique, rotate sites when applicable, and log missed doses, reactions, and inventory changes.

05 · How it works

How This Works

Epitalon (also known as Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed from the naturally occurring pineal peptide epithalamin [1] .

Research indicates it may support telomerase activation, circadian rhythm regulation, and anti-aging pathways [2] [3] .

Clinical studies employ short intermittent cycles (10–20 days) repeated 1–2 times annually [4] , though extended titration protocols are also explored for research purposes.

The library page pairs that educational context with calculator-ready vial math, so users can understand the protocol structure and then track their own entered values in one place.

06 · Daily habits

Lifestyle Factors

  • Keep meals, training, sleep, and recovery notes in the journal so trends are easier to review.
  • Track body metrics only if they are relevant to the user's goal and approved data sources.
  • Use consistent timing and logging habits so adherence data is meaningful.

07 · What to expect

Potential Benefits & Side Effects

  • Observations from preclinical and clinical research literature.

08 · Technique

Injection Technique

Pre-injection preparation
  • Wash hands with soap and water.
  • Wipe the vial stopper and chosen site with alcohol, then let both dry.
  • Confirm the vial concentration, calculator result, and intended draw amount before loading the syringe.
Injection procedure
  • Use the route and needle technique directed by a qualified professional or product instructions.
  • For subcutaneous injections, rotate sites and inject slowly to limit leakage and irritation.
  • Do not reuse needles or syringes.
Post-injection care
  • Dispose of sharps in a puncture-resistant container.
  • Return stored items promptly to the correct temperature.
  • Log dose, site, date, time, inventory change, and any observation.

09 · Evidence

References

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