Protocol
HMG (75iu Vial)
Complete dosage protocol and reconstitution guide for HMG (75iu Vial).
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01 · At a glance
Quickstart Highlights
Human Menopausal Gonadotropin (HMG) is a purified gonadotropin preparation containing equal amounts of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity [1] [2] . In males, HMG is used alongside hCG to stimulate spermatogenesis in cases of hypogonadotropic hypogonadism or infertility [3] [4] . This educational protocol presents a thrice-weekly subcutaneous approach for male fertility support.
02 · Dosing & reconstitution
Dosing & Reconstitution Guide
A practical calculator-ready setup based on the imported protocol reference. Use these values as a math starting point, then verify every entry against your own vial, diluent, and professional guidance.
Standard / Gradual Titration
Reference dose shown on this page: See guide.
Reconstitution Steps
- Draw 3.0 mL bacteriostatic water with a sterile 3 mL syringe.
- Inject slowly down the vial wall to avoid foaming.
- Gently swirl or roll the vial until fully dissolved (do not shake).
- Label with date and time; refrigerate at 2–8 °C (35.6–46.4 °F) , protected from light.
- For optimal potency, use reconstituted solution promptly or within a few days [9] .
03 · What you'll need
Supplies Needed
Keep this as a planning checklist. TNHL does not sell or verify supplies on this page, and no supplier quality claims are made here.
- per week ×
- 12 weeks)
- 16 weeks ≈ 48 vials (3
- per week ×
- 12 weeks (36 vials): 108 mL → 4 × 30 mL bottles
- 16 weeks (48 vials): 144 mL → 5 × 30 mL bottles
- Per week: 6 swabs (2
- per injection day)
- 12 weeks: 72 swabs → recommend 1 × 100-count box
- 16 weeks: 96 swabs → recommend 1 × 100-count box
Protocol Overview
- Goal: Stimulate spermatogenesis in males with hypogonadotropic hypogonadism or infertility [3] [4] .
- Schedule: Subcutaneous injections three times weekly for minimum 12 weeks (extend to 16 weeks if needed) [7] . Dose: 75 IU (0.15 mg) per injection, typically combined with hCG therapy [5] [6] .
- Reconstitution: 3.0 mL per 75 IU vial (25 IU/mL) for calculation convenience.
- Storage: Lyophilized refrigerated; reconstituted solution used promptly or within days when refrigerated.
Dosing Protocol
- Standard male fertility support approach.
- Dose: 75 IU three times per week (e.g., Monday, Wednesday, Friday).
- Combination Therapy: Usually administered alongside hCG (2–3 times weekly) to support testosterone and maximize spermatogenesis [5] [6] .
- Cycle Length: Minimum 12 weeks; may extend to 16 weeks based on response [7] .
- Route: Subcutaneous injection into fatty tissue (abdomen, thigh, or upper arm) [8] .
- Timing: Maintain consistent injection days; rotate sites with each injection.
Storage Instructions
- Lyophilized: refrigerate at 2–8 °C (35.6–46.4 °F) ; after reconstitution, use promptly or refrigerate and use within a few days.
- Storage: Lyophilized refrigerated; reconstituted solution used promptly or within days when refrigerated.
- Keep mixed and unmixed items clearly labeled so inventory and dose logs stay accurate.
04 · Good to know
Important Notes
- This HMG page is for educational research organization only.
- Confirm route, dose, contraindications, monitoring, storage, and cycle decisions with qualified professional guidance.
- Use sterile technique, rotate sites when applicable, and log missed doses, reactions, and inventory changes.
05 · How it works
How This Works
Human Menopausal Gonadotropin (HMG) is a purified gonadotropin preparation containing equal amounts of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity [1] [2] .
In males, HMG is used alongside hCG to stimulate spermatogenesis in cases of hypogonadotropic hypogonadism or infertility [3] [4] .
This educational protocol presents a thrice-weekly subcutaneous approach for male fertility support.
The library page pairs that educational context with calculator-ready vial math, so users can understand the protocol structure and then track their own entered values in one place.
06 · Daily habits
Lifestyle Factors
- Keep meals, training, sleep, and recovery notes in the journal so trends are easier to review.
- Track body metrics only if they are relevant to the user's goal and approved data sources.
- Use consistent timing and logging habits so adherence data is meaningful.
07 · What to expect
Potential Benefits & Side Effects
- Observations from clinical fertility literature.
08 · Technique
Injection Technique
- Wash hands with soap and water.
- Wipe the vial stopper and chosen site with alcohol, then let both dry.
- Confirm the vial concentration, calculator result, and intended draw amount before loading the syringe.
- Use the route and needle technique directed by a qualified professional or product instructions.
- For subcutaneous injections, rotate sites and inject slowly to limit leakage and irritation.
- Do not reuse needles or syringes.
- Dispose of sharps in a puncture-resistant container.
- Return stored items promptly to the correct temperature.
- Log dose, site, date, time, inventory change, and any observation.
09 · Evidence