Protocol
SLU-PP-332 (5mg Vial)
Complete dosage protocol and reconstitution guide for SLU-PP-332 (5mg Vial).
Calculator preset
Run the vial math before tracking.
At ~1.67 mg/mL, 1 unit ~ 16.67 mcg ; 625 mcg ~ 37.5 units and 1,250 mcg ~ 75 units on a U-100 syringe.
01 · At a glance
Quickstart Highlights
PRECLINICAL RESEARCH COMPOUND: SLU-PP-332 is a synthetic pan-agonist of estrogen-related receptors (ERRα/β/γ) studied exclusively in murine models for its ability to activate an aerobic-exercise gene program, enhance mitochondrial function, and improve endurance and cardiometabolic phenotypes [1] [2] [3] . No human trials have been conducted as of November 2025. This educational protocol reflects published murine regimens using intraperitoneal administration. Evidence Base: Preclinical only—in vivo mouse studies with intraperitoneal dosing (25–50 mg/kg twice daily).
02 · Dosing & reconstitution
Dosing & Reconstitution Guide
A practical calculator-ready setup based on the imported protocol reference. Use these values as a math starting point, then verify every entry against your own vial, diluent, and professional guidance.
Standard / Gradual Titration
Reference dose shown on this page: 1.67 mg.
Reconstitution Steps
- Draw 3.0 mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall; avoid foaming.
- Gently swirl/roll until dissolved (do not shake).
- Label and refrigerate at 2–8 °C (35.6–46.4 °F) , protected from light.
03 · What you'll need
Supplies Needed
Keep this as a planning checklist. TNHL does not sell or verify supplies on this page, and no supplier quality claims are made here.
- 12 weeks ≈ 39 vials
- 16 weeks ≈ 53 vials
- 8 weeks: 112 syringes
- 12 weeks: 168 syringes
- 16 weeks: 224 syringes
- 8 weeks (25 vials): 75 mL → 8 × 10 mL bottles
- 12 weeks (39 vials): 117 mL → 12 × 10 mL bottles
- 16 weeks (53 vials): 159 mL → 16 × 10 mL bottles
- Per week: 28 swabs (4/day)
- 8 weeks: 224 swabs → recommend 3 × 100-count boxes
- 12 weeks: 336 swabs → recommend 4 × 100-count boxes
- 16 weeks: 448 swabs → recommend 5 × 100-count boxes
Protocol Overview
- Reconstitution: 3.0 mL per 5 mg vial (~1.67 mg/mL).
- Storage: Lyophilized frozen; reconstituted refrigerated.
Dosing Protocol
- Murine-equivalent dosing framework.
- Initial Phase (Weeks 1–2): 1250 mcg daily (625 mcg per injection, twice daily).
- Maintenance Phase (Weeks 3–8): 2500 mcg daily (1250 mcg per injection, twice daily).
- Frequency: Twice per day, reflecting published murine regimens [1] [2] [3] .
- Route: Intraperitoneal (as studied in preclinical models).
- Timing: Consistent intervals between administrations.
Storage Instructions
- Lyophilized: −20 °C (−4 °F) ; reconstituted: 2–8 °C (35.6–46.4 °F) .
- Storage: Lyophilized frozen; reconstituted refrigerated.
- Keep mixed and unmixed items clearly labeled so inventory and dose logs stay accurate.
04 · Good to know
Important Notes
- This SLU-PP-332 page is for educational research organization only.
- Confirm route, dose, contraindications, monitoring, storage, and cycle decisions with qualified professional guidance.
- Use sterile technique, rotate sites when applicable, and log missed doses, reactions, and inventory changes.
05 · How it works
How This Works
PRECLINICAL RESEARCH COMPOUND: SLU-PP-332 is a synthetic pan-agonist of estrogen-related receptors (ERRα/β/γ) studied exclusively in murine models for its ability to activate an aerobic-exercise gene program, enhance mitochondrial function, and improve endurance and cardiometabolic phenotypes [1] [2] [3] .
No human trials have been conducted as of November 2025.
This educational protocol reflects published murine regimens using intraperitoneal administration.
The library page pairs that educational context with calculator-ready vial math, so users can understand the protocol structure and then track their own entered values in one place.
06 · Daily habits
Lifestyle Factors
- Keep meals, training, sleep, and recovery notes in the journal so trends are easier to review.
- Track body metrics only if they are relevant to the user's goal and approved data sources.
- Use consistent timing and logging habits so adherence data is meaningful.
07 · What to expect
Potential Benefits & Side Effects
- Findings from murine studies only.
- Metabolic effects: Enhanced mitochondrial function, increased fatty-acid oxidation, improved glucose tolerance in diet-induced obese mice [2] .
- Cardiac benefits: Ameliorated heart failure through enhanced cardiac fatty-acid metabolism and mitochondrial function in preclinical models [3] .
- Endurance enhancement: Increased treadmill running capacity and muscle oxidative capacity in mice [1] .
- Renal effects: Reversed mitochondrial dysfunction and inflammation in aging kidney models [4] .
- Human safety unknown: No data on human tolerability, pharmacokinetics, or adverse effects exist.
08 · Technique
Injection Technique
- Wash hands with soap and water.
- Wipe the vial stopper and chosen site with alcohol, then let both dry.
- Confirm the vial concentration, calculator result, and intended draw amount before loading the syringe.
- Use the route and needle technique directed by a qualified professional or product instructions.
- For subcutaneous injections, rotate sites and inject slowly to limit leakage and irritation.
- Do not reuse needles or syringes.
- Dispose of sharps in a puncture-resistant container.
- Return stored items promptly to the correct temperature.
- Log dose, site, date, time, inventory change, and any observation.
09 · Evidence